Degrado, William F : rechercher sur Z-Library

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1

Packing of apolar side chains enables accurate design of highly stable membrane proteins

Mravic, Marco, Thomaston, Jessica L., Tucker, Maxwell, Solomon, Paige E., Liu, Lijun, DeGrado, William F.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2019

2

Foldamers as versatile frameworks for the design and evolution of function

Goodman, Catherine M, Choi, Sungwook, Shandler, Scott, DeGrado, William F

Journal:

Nature Chemical Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1024 KB

english, 2007

3

Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs

Alessandro Senes, Donald E Engel, William F DeGrado

Journal:

Current Opinion in Structural Biology

Année:

2004

Langue:

english

Fichier:

PDF, 601 KB

english, 2004

4

Transmembrane Communication: General Principles and Lessons from the Structure and Function of the M2 Proton Channel, K + Channels, and Integrin Receptors

Grigoryan, Gevorg, Moore, David T., DeGrado, William F.

Journal:

Annual Review of Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2011

5

Artificial diiron proteins: From structure to function

Jennifer R. Calhoun, Flavia Nastri, Ornella Maglio, Vincenzo Pavone, Angela Lombardi, William F. DeGrado

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 661 KB

english, 2005

6

Synthesis and per-functionalization of heptakis(6-O-carboxymethyl-2,3-di-O-methyl)cyclomaltoheptaose

Karin S. Åkerfeldt, William F. DeGrado

Journal:

Tetrahedron Letters

Année:

1994

Langue:

english

Fichier:

PDF, 384 KB

english, 1994

7

Salt bridges: Geometrically specific, designable interactions

Jason E. Donald, Daniel W. Kulp, William F. DeGrado

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2011

Langue:

english

Fichier:

PDF, 837 KB

english, 2011

8

Sequence and structural homologies among type I and type II interferons

DeGrado, William F., Wasserman, Zelda R., Chowdhry, Vinay

Journal:

Année:

1982

Fichier:

PDF, 353 KB

1982

9

Structural basis for the function and inhibition of an influenza virus proton channel

Stouffer, Amanda L., Acharya, Rudresh, Salom, David, Levine, Anna S., Di Costanzo, Luigi, Soto, Cinque S., Tereshko, Valentina, Nanda, Vikas, Stayrook, Steven, DeGrado, William F.

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 766 KB

english, 2008

10

Discovery of a Potent Thiadiazole Class of Histamine H3 Receptor Antagonist for the Treatment of Diabetes

Rao, Ashwin U., Shao, Ning, Aslanian, Robert G., Chan, Tin-Yau, Degrado, Sylvia J., Wang, Li, McKittrick, Brian, Senior, Mary, West, Robert E., Williams, Shirley M.

Journal:

ACS Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 3.36 MB

english, 2012

11

Infrared Spectra of Amide Groups in α-Helical Proteins: Evidence for Hydrogen Bonding between Helices and Water

Manas, Eric S., Getahun, Zelleka, Wright, Wayne W., DeGrado, William F., Vanderkooi, Jane M.

Journal:

Journal of the American Chemical Society

Année:

2000

Langue:

english

Fichier:

PDF, 167 KB

english, 2000

12

Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus

Jun Wang, Jade Xiaoyan Qiu, Cinque Soto, William F DeGrado

Journal:

Current Opinion in Structural Biology

Année:

2011

Langue:

english

Fichier:

PDF, 934 KB

english, 2011

13

Solution NMR Structure of a Designed Metalloprotein and Complementary Molecular Dynamics Refinement

Jennifer R. Calhoun, Weixia Liu, Katrin Spiegel, Matteo Dal Peraro, Michael L. Klein, Kathleen G. Valentine, A. Joshua Wand, William F. DeGrado

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 818 KB

english, 2008

14

The Interplay of Functional Tuning, Drug Resistance, and Thermodynamic Stability in the Evolution of the M2 Proton Channel from the Influenza A Virus

Amanda L. Stouffer, Chunlong Ma, Lidia Cristian, Yuki Ohigashi, Robert A. Lamb, James D. Lear, Lawrence H. Pinto, William F. DeGrado

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 733 KB

english, 2008

15

De Novo Design of Antimicrobial Polymers, Foldamers, and Small Molecules: From Discovery to Practical Applications

Tew, Gregory N., Scott, Richard W., Klein, Michael L., DeGrado, William F.

Journal:

Accounts of Chemical Research

Année:

2010

Langue:

english

Fichier:

PDF, 2.32 MB

english, 2010

16

β-Peptides: From Structure to Function

Cheng, Richard P., Gellman, Samuel H., DeGrado, William F.

Journal:

Chemical Reviews

Année:

2001

Langue:

english

Fichier:

PDF, 335 KB

english, 2001

17

Nature-inspired design of motif-specific antibody scaffolds

Koerber, James T, Thomsen, Nathan D, Hannigan, Brett T, Degrado, William F, Wells, James A

Journal:

Nature Biotechnology

Année:

2013

Langue:

english

Fichier:

PDF, 952 KB

english, 2013

18

DE NOVO DESIGN AND STRUCTURAL CHARACTERIZATION OF PROTEINS AND METALLOPROTEINS

DeGrado, William F., Summa, Christopher M., Pavone, Vincenzo, Nastri, Flavia, Lombardi, Angela

Journal:

Annual Review of Biochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 2.97 MB

english, 1999

19

Cys-Scanning Disulfide Crosslinking and Bayesian Modeling Probe the Transmembrane Signaling Mechanism of the Histidine Kinase, PhoQ

Molnar, Kathleen S., Bonomi, Massimiliano, Pellarin, Riccardo, Clinthorne, Graham D., Gonzalez, Gabriel, Goldberg, Shalom D., Goulian, Mark, Sali, Andrej, DeGrado, William F.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 3.13 MB

english, 2014

20

Toward the Synthesis of a Photosynthetic Reaction Center Maquette: A Cofacial Porphyrin Pair Assembled between Two Subunits of a Synthetic Four-Helix Bundle Multiheme Protein

Rabanal, Francesc, DeGrado, William F., Dutton, P. Leslie

Journal:

Journal of the American Chemical Society

Année:

1996

Langue:

english

Fichier:

PDF, 146 KB

english, 1996

21

Signal Transduction in Histidine Kinases: Insights from New Structures

Bhate, Manasi P., Molnar, Kathleen S., Goulian, Mark, DeGrado, William F.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 4.35 MB

english, 2015

22

Metal ion-dependent modulation of the dynamics of a designed protein

Handel, T., Williams, S., DeGrado, W.

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.76 MB

english, 1993

23

Influenza A M2 Inhibitor Binding Understood through Mechanisms of Excess Proton Stabilization and Channel Dynamics

Watkins, Laura C, DeGrado, William F., Voth, Gregory A.

Journal:

Journal of the American Chemical Society

Année:

2020

Fichier:

PDF, 6.87 MB

2020

24

Prion biology: implications for Alzheimer's disease therapeutics

Condello, Carlo, DeGrado, William F, Prusiner, Stanley B

Journal:

The Lancet Neurology

Année:

2020

Fichier:

PDF, 68 KB

2020

25

The role of helix formation in the folding of a fully α-helical coiled coil

Sosnick, Tobin R., Jackson, Sharon, Wilk, Rosemarie R., Englander, S. Walter, DeGrado, William F.

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1996

Langue:

english

Fichier:

PDF, 652 KB

english, 1996

26

De novo design of heterotrimeric coiled coils

Angela Lombardi, James W. Bryson, William F. DeGrado

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 766 KB

english, 1996

27

Structural consequences of an amino acid deletion in the B1 domain of protein G

Karyn T. O'Neil, Alvin C. Bach II, William F. DeGrado

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2000

Langue:

english

Fichier:

PDF, 319 KB

english, 2000

28

Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability

Yi Tang, Giovanna Ghirlanda, Wendy A. Petka, Tadashi Nakajima, William F. DeGrado, David A. Tirrell

Journal:

Angewandte Chemie

Année:

2001

Langue:

english

Fichier:

PDF, 85 KB

english, 2001

29

Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability

Yi Tang, Giovanna Ghirlanda, Wendy A. Petka, Tadashi Nakajima, William F. DeGrado, David A. Tirrell

Journal:

Angewandte Chemie International Edition

Année:

2001

Langue:

english

Fichier:

PDF, 85 KB

english, 2001

30

Nontoxic Membrane-Active Antimicrobial Arylamide Oligomers

Dahui Liu, Sungwook Choi, Bin Chen, Robert J. Doerksen, Dylan J. Clements, Jeffrey D. Winkler, Michael L. Klein, William F. DeGrado

Journal:

Angewandte Chemie

Année:

2004

Langue:

english

Fichier:

PDF, 177 KB

english, 2004

31

Sliding Helix and Change of Coordination Geometry in a Model Di-MnII Protein

William F. DeGrado, Luigi Di Costanzo, Silvano Geremia, Angela Lombardi, Vincenzo Pavone, Lucio Randaccio

Journal:

Angewandte Chemie

Année:

2003

Langue:

english

Fichier:

PDF, 188 KB

english, 2003

32

Titelbild: Nontoxic Membrane-Active Antimicrobial Arylamide Oligomers (Angew. Chem. 9/2004)

Dahui Liu, Sungwook Choi, Bin Chen, Robert J. Doerksen, Dylan J. Clements, Jeffrey D. Winkler, Michael L. Klein, William F. DeGrado

Journal:

Angewandte Chemie

Année:

2004

Fichier:

PDF, 21 KB

2004

33

The Design and Evaluation of Heparin-Binding Foldamers

Sungwook Choi, Dylan J. Clements, Vojislava Pophristic, Ivaylo Ivanov, Satyavani Vemparala, Joel S. Bennett, Michael L. Klein, Jeffrey D. Winkler, William F. DeGrado

Journal:

Angewandte Chemie

Année:

2005

Langue:

english

Fichier:

PDF, 182 KB

english, 2005

34

Titelbild: The Design and Evaluation of Heparin-Binding Foldamers (Angew. Chem. 41/2005)

Sungwook Choi, Dylan J. Clements, Vojislava Pophristic, Ivaylo Ivanov, Satyavani Vemparala, Joel S. Bennett, Michael L. Klein, Jeffrey D. Winkler, William F. DeGrado

Journal:

Angewandte Chemie

Année:

2005

Langue:

german

Fichier:

PDF, 62 KB

german, 2005

35

The Structure of a Designed Diiron(III) Protein: Implications for Cofactor Stabilization and Catalysis

Herschel Wade, Steven E. Stayrook, William F. DeGrado

Journal:

Angewandte Chemie

Année:

2006

Langue:

english

Fichier:

PDF, 345 KB

english, 2006

36

Role of the Conformational Rigidity in the Design of Biomimetic Antimicrobial Compounds

Andrey Ivankin, Liran Livne, Prof. Amram Mor, Prof. Gregory A. Caputo, Prof. William F. DeGrado, Dr. Mati Meron, Dr. Binhua Lin, Prof. David Gidalevitz

Journal:

Angewandte Chemie

Année:

2010

Langue:

english

Fichier:

PDF, 530 KB

english, 2010

37

Design of a Three-Helix Bundle Capable of Binding Heavy Metals in a Triscysteine Environment

Saumen Chakraborty, Dr. Joslyn Yudenfreund Kravitz, Prof. Peter W. Thulstrup, Prof. Lars Hemmingsen, Prof. William F. DeGrado, Prof. Vincent L. Pecoraro

Journal:

Angewandte Chemie

Année:

2011

Langue:

english

Fichier:

PDF, 373 KB

english, 2011

38

Innentitelbild: Design of a Three-Helix Bundle Capable of Binding Heavy Metals in a Triscysteine Environment (Angew. Chem. 9/2011)

Saumen Chakraborty, Dr. Joslyn Yudenfreund Kravitz, Prof. Peter W. Thulstrup, Prof. Lars Hemmingsen, Prof. William F. DeGrado, Prof. Vincent L. Pecoraro

Journal:

Angewandte Chemie

Année:

2011

Fichier:

PDF, 560 KB

2011

39

Nontoxic Membrane-Active Antimicrobial Arylamide Oligomers

Dahui Liu, Sungwook Choi, Bin Chen, Robert J. Doerksen, Dylan J. Clements, Jeffrey D. Winkler, Michael L. Klein, William F. DeGrado

Journal:

Angewandte Chemie International Edition

Année:

2004

Langue:

english

Fichier:

PDF, 178 KB

english, 2004

40

Sliding Helix and Change of Coordination Geometry in a Model Di-MnII Protein

William F. DeGrado, Luigi Di Costanzo, Silvano Geremia, Angela Lombardi, Vincenzo Pavone, Lucio Randaccio

Journal:

Angewandte Chemie International Edition

Année:

2003

Langue:

english

Fichier:

PDF, 188 KB

english, 2003

41

Cover Picture: Nontoxic Membrane-Active Antimicrobial Arylamide Oligomers (Angew. Chem. Int. Ed. 9/2004)

Dahui Liu, Sungwook Choi, Bin Chen, Robert J. Doerksen, Dylan J. Clements, Jeffrey D. Winkler, Michael L. Klein, William F. DeGrado

Journal:

Angewandte Chemie International Edition

Année:

2004

Fichier:

PDF, 21 KB

2004

42

The Design and Evaluation of Heparin-Binding Foldamers

Sungwook Choi, Dylan J. Clements, Vojislava Pophristic, Ivaylo Ivanov, Satyavani Vemparala, Joel S. Bennett, Michael L. Klein, Jeffrey D. Winkler, William F. DeGrado

Journal:

Angewandte Chemie International Edition

Année:

2005

Langue:

english

Fichier:

PDF, 182 KB

english, 2005

43

Cover Picture: The Design and Evaluation of Heparin-Binding Foldamers (Angew. Chem. Int. Ed. 41/2005)

Sungwook Choi, Dylan J. Clements, Vojislava Pophristic, Ivaylo Ivanov, Satyavani Vemparala, Joel S. Bennett, Michael L. Klein, Jeffrey D. Winkler, William F. DeGrado

Journal:

Angewandte Chemie International Edition

Année:

2005

Langue:

english

Fichier:

PDF, 61 KB

english, 2005

44

Role of the Conformational Rigidity in the Design of Biomimetic Antimicrobial Compounds

Andrey Ivankin, Liran Livne, Prof. Amram Mor, Prof. Gregory A. Caputo, Prof. William F. DeGrado, Dr. Mati Meron, Dr. Binhua Lin, Prof. David Gidalevitz

Journal:

Angewandte Chemie International Edition

Année:

2010

Langue:

english

Fichier:

PDF, 549 KB

english, 2010

45

Design of a Three-Helix Bundle Capable of Binding Heavy Metals in a Triscysteine Environment

Saumen Chakraborty, Dr. Joslyn Yudenfreund Kravitz, Prof. Peter W. Thulstrup, Prof. Lars Hemmingsen, Prof. William F. DeGrado, Prof. Vincent L. Pecoraro

Journal:

Angewandte Chemie International Edition

Année:

2011

Langue:

english

Fichier:

PDF, 363 KB

english, 2011

46

Inside Cover: Design of a Three-Helix Bundle Capable of Binding Heavy Metals in a Triscysteine Environment (Angew. Chem. Int. Ed. 9/2011)

Saumen Chakraborty, Dr. Joslyn Yudenfreund Kravitz, Prof. Peter W. Thulstrup, Prof. Lars Hemmingsen, Prof. William F. DeGrado, Prof. Vincent L. Pecoraro

Journal:

Angewandte Chemie International Edition

Année:

2011

Fichier:

PDF, 583 KB

2011

47

Dedication

Murray Goodman, William DeGrado

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 126 KB

english, 1990

48

Peptide models for the membrane destabilizing actions of viral fusion proteins

Richard M. Epand, James J. Cheetham, Raquel F. Epand, Philip L. Yeagle, Christopher D. Richardson, Arlene Rockwell, William F. Degrado

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 493 KB

english, 1992

49

Controlling the Conformation of Arylamides: Computational Studies of Intramolecular Hydrogen Bonds between Amides and Ethers or Thioethers

Robert J. Doerksen, Bin Chen, Dahui Liu, Gregory N. Tew, William F. DeGrado, Michael L. Klein

Journal:

Chemistry - A European Journal

Année:

2004

Langue:

english

Fichier:

PDF, 263 KB

english, 2004

50

The Role of Hydrophobicity in the Antimicrobial and Hemolytic Activities of Polymethacrylate Derivatives

Kenichi Kuroda, Gregory A. Caputo, William F. DeGrado

Journal:

Chemistry - A European Journal

Année:

2009

Langue:

english

Fichier:

PDF, 440 KB

english, 2009